Signaling via Vascular Endothelial Growth Factor Receptors
Identifieur interne : 00AC81 ( Main/Exploration ); précédent : 00AC80; suivant : 00AC82Signaling via Vascular Endothelial Growth Factor Receptors
Auteurs : Tatiana V. Petrova [Finlande] ; Taija Makinen [Finlande] ; Kari Alitalo [Finlande]Source :
- Experimental Cell Research [ 0014-4827 ] ; 1999.
English descriptors
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Abstract
Angiogenesis, or development of blood vessels from preexisting vasculature, has important functions under both normal and pathophysiological conditions. Vascular endothelial growth factor receptors 1–3, also known as flt-1, KDR, and flt-4, are endothelial cell-specific receptor tyrosine kinases which serve as key mediators of the angiogenic responses. The review focuses on the signaling pathways that are initiated from these receptors and the recently identified VEGF coreceptor neuroplilin-1.
Url:
DOI: 10.1006/excr.1999.4707
Affiliations:
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Vascular endothelial growth factor receptors 1–3, also known as flt-1, KDR, and flt-4, are endothelial cell-specific receptor tyrosine kinases which serve as key mediators of the angiogenic responses. The review focuses on the signaling pathways that are initiated from these receptors and the recently identified VEGF coreceptor neuroplilin-1.</div></front></TEI><affiliations><list><country><li>Finlande</li></country><region><li>Uusimaa</li></region><settlement><li>Helsinki</li></settlement><orgName><li>Université d'Helsinki</li></orgName></list><tree><country name="Finlande"><region name="Uusimaa"><name sortKey="Petrova, Tatiana V" sort="Petrova, Tatiana V" uniqKey="Petrova T" first="Tatiana V." last="Petrova">Tatiana V. 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